News Archive

April 5, 2018

We are excited to welcome Chiara Ruggeri to the lab! Chiara is an NCCR RNA & Disease Predoc rotation student and will spend her second stage with us.

March 29, 2018

Today was Veronika’s last day in the lab :(. We wish you all the best for your next steps, take care!

February 19, 2018

New paper published in Genes & Development on the role of Zc3h13/Flacc in depositing adenine methylation (m6A) on RNAs. Check it out this great work achieved in collaboration with the Roignant lab (IMB, Mainz):

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d

Screen Shot 2018-03-19 at 18.26.49


February 18, 2018

Pics from the FMI Skiweekend :).



November 22, 2017

Veronika Ostapcuk successfully defended her PhD thesis! Congrats Dr. Ostapcuk!


November 17, 2017

Today was Vale’s last day in the lab :(. Take care and all the best for the future!


November 1, 2017

We welcome our new PhD student Aparna Pandey to the lab!


October 30, 2017

Tahsin got himself a brand new bike! After fat bikes such curved bikes are the latest development on the MTB market. Good stuff.


September 29, 2017

Lisa had her last day and will move on to carry out her masters thesis. All the best and good luck in the UK!


September 11, 2017

The FMI selection has won the renown Basel Science Soccer Cup 2017 ! Of course, the Buehler lab helped to defeat the teams from D-BSSE and Biocenter :).



August 2, 2017

Today, Gizem Incekara started her masters thesis in the lab. Welcome and all the best!


July 1, 2017

Today, Lisa Lampersberger started her internship in the lab. Welcome and all the best!


June 26, 2017

New lab paper in Molecular Cell on the role of Mst2 in preventing ectopic heterochromatin formation.

“The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.” Flury et al, 2017


June 6, 2017


Today Valentin successfully defended his PhD thesis entitled “A euchromatic feedback loop prevents heterochromatin formation”. Congrats Dr. Flury!





June 5, 2017

Screen Shot 2017-06-07 at 15.40.18

New lab paper on the function of the RNA modification m6A during heat shock response appeared today in Nature Structural & Molecular Biology.

Knuckles et al. “RNA fate determination through cotranscriptional adenosine methylation and microprocessor binding”. NSMB. 2017.

Read the official FMI press release here.


May 17, 2017


Sad news. So sad: Our beloved Primulae died despite daily watering. Nevertheless, they have survived for 3 months.




April, 3, 2017


Tahsin quickly adopted the yeast crew clothing style. Btw, Vale’s shirt was white, too, when he started his PhD…

April 1, 2017

We welcome our new lab member Tahsin Kuzdere! Today is the official start of his PhD (no joke). Good luck!

February 15, 2017

Our latest additions… Survival estimates range from 2 days to 5 years. What is your guess? Post it at the bottom of this page.


January 2, 2017

Today, Lucas Kaaij started his postdoc in the lab. Welcome and all the best!

December 22, 2016


New lab paper providing mechanistic insights into small RNA mediated gene silencing was published today in Genes & Development! Have a look.

November 16, 2016

New paper on the mechanisms that shape piRNA 3’ends appeared today. Check it out!

November 9, 2016

Apply now for the FMI PhD program!

Deadline is November 20, 2016. Use the following link to get to the offical online application page:

September 5, 2016

Both Buehler lab teams finished among the top 3 FMI teams in the Global Coorporate Challange (GCC). Over the past 100 days we have accomplished over 14’100 km!

Screen Shot 2016-09-05 at 14.55.14.png

August 30, 2016

The Bühler Lab Knife was on tour again . This time with Claudi in the Swiss alps. Click here for more pics.

July 17, 2016


Matyas Flemr has successfully conquered the 101 km Eiger Ultra

Trail within 17 hours 36 minutes and 47 seconds. Amazing. Congrats!





June 1, 2016

Lea Dümpelmann started her PhD in our lab. Welcome and good luck !

May 17, 2016

Recently, somewhere in Nepal: Rodrigo, a former PhD student, is looking for a suitable spot for an outstation of the lab.



May, 13, 2016

Research section updated. Have a look!

April 1, 2016

We welcome Tahsin Kuzdere, who will do his Masters Thesis in our lab.

March 31, 2016

Today was Rodrigo’s last day in the lab. Enjoy the vacation and all the best for the new position in Zürich!

February 9, 2016

Alex was just awarded the Benchling Gold status! Congrats! (Irrespective of this mind blowing honor, Benchling indeed is a great tool for sequence managing, manipulation, alignment, in silico cloning, etc.)

February 2, 2016

TALEN design and cloning protocol online now!

February 1, 2016

Check out the pics from our lab ski trip in Flims!

December 18, 2015

Alice Wenger finished her Masters thesis! We will miss your enthusiasm and excitement :). All the best!

December 15, 2015

Marc Bühler has been awarded an ERC Consolidator grant!

December 9, 2015

Today, Rodrigo defended his PhD. Congrats Dr. Villasenor Mollino!

November 30, 2015

After successfully finishing her PhD, Kasia Kowalik left us and took up a new challenge. All the best!

October 30, 2015

Silke Lochs successfully finished her Master Internship. We wish her all the best for the future!

October 5, 2015

New group paper on the role of HP1/Swi6 in delimiting H3K9me spreading into euchromatic regions adjacent to constitutive hereochromatin. (H3K9 methylation extends across natural boundaries of heterochromatin in the absence of an HP1 protein. Stunnenberg et al, ).

September 16 – 18, 2015

We are at the annual meeting in Grindelwald (see pics).

August 31- September 2, 2015

Bühler lab retreat in La Neuveville (see pics).

July 16, 2015

New paper describing a simple and efficient method to generate knock-out and knock-in embryonic stem cells published in Cell Reports (Flemr and Bühler, Single step generation of conditional knock out mouse embryonic stem cells. Cell Rep., 2015 Jul; 12(4):709-16).

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